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Under certain conditions, GGT-mediated degradation of GSH facilitates the formation of reactive oxygen species, causing lipid peroxidation of cell membranes, which ultimately leads to apoptosis or necrosis of gastric epithelial cells in vitro 15

Off-label veterinary use and animal studies indicate that it is in general well tolerated, although it is not FDA approved for dogs , and should only be used under veterinary supervision

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